Hold a vote of no confidence in Her Majesty's Government as soon as possible.

It's clear that the Brexit deadlock is not going to be resolved by either HM's Government or Opposition, and joint efforts to hold such a vote by the SNP, Greens, Plaid Cymru and Lib-Dems have been dismissed and refused. We, the people need to call for an end to the deadlock before it is too late.

We can't accept petitions about appointments, which includes calling for Ministers, including the Prime Minister, to be sacked or for a vote of no confidence.

We used to accept petitions that called for a vote of no confidence. However, the Petitions Committee can’t schedule votes of no confidence. This was often frustrating and disappointing for petitioners.

If you're concerned about a particular policy or decision that's the responsibility of Government or the House of Commons, you could start a petition about that.
Petitions calling for action on policy are more likely to be an effective way of achieving the change you want.