Public vote of no confidence in Theresa May, replace our PM immediately.

The prime minister has mislead and refused to deliver accurately what was promised as part of the deal to allow the citizens of the UK to decide our future relationship with the EU. She must step aside and enable a no conflicting candidate continue with delivering on the result of the referendum.

We can't accept petitions about appointments, which includes calling for a vote of no confidence.

We used to accept petitions that called for a vote of no confidence. However, the Petitions Committee can’t schedule votes of no confidence. This was often frustrating and disappointing for petitioners.

If you're concerned about a particular policy or decision that's the responsibility of Government or the House of Commons, you could start a petition about that.
Petitions calling for action on policy are more likely to be an effective way of achieving the change you want.